ABSTRACT
Background: Oral health assessment played a pivotal role in preventive dentistry, and cytological analysis of exfoliated gingival cells emerged as a valuable tool for understanding the cellular dynamics of the oral mucosa. This study aimed to investigate the quantitative aspects of cytomorphometry in normal exfoliated gingival cells to enhance our understanding of oral health indicators.
Aim: The primary objective of this comprehensive study was to quantify and analyze the morphological characteristics of normal exfoliated gingival cells, with a focus on identifying cellular parameters indicative of oral health. By establishing baseline cytological measurements, the aim was to contribute to the development of effective diagnostic and preventive strategies for oral diseases.
Methods: A diverse cohort of individuals with good oral health was recruited for the study. Exfoliated gingival cells were collected through non-invasive techniques, and cytological smears were prepared for analysis. The research was carried out at Mayo Hospital Lahore from January 2023 to January 2024. Digital imaging and advanced software tools were employed for cytomorphometric measurements, including cell size, nuclear size, nuclear-cytoplasmic ratio, and other relevant parameters. Statistical analyses were performed to determine correlations and significance.
Results: The study was expected to yield comprehensive quantitative data on the cytomorphometry of normal exfoliated gingival cells. Preliminary analyses suggested that specific cellular parameters may serve as reliable indicators of oral health status. The results were presented with visual representations, charts, and statistical comparisons, providing valuable insights into the cellular characteristics associated with optimal oral health.
Conclusion: This research shed light on the quantitative aspects of cytomorphometry in normal exfoliated gingival cells and their significance in assessing oral health. The identified cellular parameters may serve as potential biomarkers for early detection and monitoring of oral diseases. The findings contributed to the ongoing efforts to enhance oral health diagnostics and preventive strategies, promoting overall well-being.
Keywords: Cytomorphometry, exfoliated gingival cells, oral health assessment, quantitative analysis, cellular parameters, biomarkers, preventive dentistry, diagnostic strategies, digital imaging, statistical analysis.