ABSTRACT:

Background: Dengue fever, a mosquito-borne viral illness, presents a significant health burden globally. Gastrointestinal bleeding (GIB) and hematocrit decline are known complications in severe cases of dengue fever, often requiring medical intervention such as blood transfusions. Understanding the correlation between GIB and hematocrit decline is crucial for identifying risk factors and determining transfusion needs in dengue fever patients, particularly in tertiary care settings where severe cases are managed.

Aim: This study aimed to explore the correlation between gastrointestinal bleeding and hematocrit decline in patients diagnosed with dengue fever within a tertiary care setting. The primary objective was to identify risk factors associated with the occurrence of GIB and hematocrit decline, while also assessing the necessity and frequency of blood transfusions in these patients.

Methods: A retrospective analysis of medical records from dengue fever patients admitted to a tertiary care facility over a specified period was conducted. Patients with documented instances of gastrointestinal bleeding and hematocrit decline were included in the study. Relevant demographic, clinical, and laboratory data were collected and analyzed to identify correlations and risk factors. Statistical methods such as logistic regression were employed to determine the strength of associations and assess predictive values.

Results: Among the dengue fever patients included in the study, a significant correlation was observed between gastrointestinal bleeding and hematocrit decline. Several risk factors, including disease severity, comorbidities, and platelet counts, were identified as predictors for these complications. Furthermore, the study revealed varying transfusion needs based on the severity of GIB and degree of hematocrit decline, highlighting the importance of individualized management strategies.

Conclusion: The findings of this study underscore the importance of recognizing and managing gastrointestinal bleeding and hematocrit decline in dengue fever patients within tertiary care settings. Identification of risk factors can aid in early intervention and appropriate allocation of resources, including blood transfusions, thereby potentially improving patient outcomes and reducing morbidity associated with severe dengue fever.

Keywords: Dengue fever, gastrointestinal bleeding, hematocrit decline, risk factors, transfusion needs, tertiary care setting.