ABSTRACT
Background: Total anomalous pulmonary venous connection (TAPVC) repair is the complex congenital heart surgery. Despite surgical advancements, reverse remodeling of left ventricle (LV) post-repair varies among patients. Identifying predictors for successful LV reverse remodeling is crucial for improving patient outcomes.
Aim: This research intended to identify predictors of reverse remodeling of left ventricle in patients who experienced TAPVC repair.
Methods: A retrospective cohort research was led from June 2023 to May 2024, involving 120 patients who underwent TAPVC repair. Data on preoperative, intraoperative, and postoperative variables were collected. Echocardiographic measurements were used to measure LV dimensions and function before surgery and at a 12-month follow-up. Statistical analyses, including multivariate regression, were performed to recognize significant predictors of LV reverse remodeling.
Results: The research comprised 120 individuals having the average age of X years (range Y-Z). Significant predictors for LV reverse remodeling post-TAPVC repair included younger age at surgery (p < 0.01), absence of preoperative pulmonary hypertension (p < 0.05), and shorter cardiopulmonary bypass time (p < 0.05). Additionally, patients with lower preoperative LV end-diastolic volume index (LVEDVI) showed more favorable reverse remodeling (p < 0.01).
Conclusion: Younger age at time of surgery, absence of preoperative pulmonary hypertension, shorter cardiopulmonary bypass time, and lower preoperative LVEDVI were significant predictors for reverse
remodeling of the left ventricle following TAPVC repair. These findings can guide preoperative assessment and surgical planning to enhance patient outcomes.
Keywords: Total anomalous pulmonary venous connection, left ventricle, reverse remodeling, predictors, congenital heart surgery, echocardiography, cardiopulmonary bypass time.