VOLUME 26 ISSUES 3 | 2024

Determination of outcomes of pregnancy (in terms of miscarriages and multiple pregnancies) in primigravidas with successful ovulation induction

 1Dr. Hina Rauf, 2Dr. Samina Khurshid, 3Dr. Adila Ashraf, 4Dr. Hania Zafar, 5Dr. Rabia d/o Zahoor Hussain, 6Dr. Anila Sabir

1Senior registrar Abu Umara medical college, Lahore
2Associate professor Abu Umara medical college, Lahore
3Assistant professor Continental medical college, Lahore
4Assistant professor Abu Umara medical college, Lahore
5Assistant professor Abu Umara medical college, Lahore
6Assistant professor Abu Umara medical college, Lahore

ABSTRACT
Introduction: Regular ovulation is associated with regular menstruation. Women with irregular periods, occasional periods or no periods will often have an ovulation disorder. When a woman with an ovulation disorder is trying to conceive, she will usually require medication to induce normal follicle development and regular ovulation. For some women who already have regular menstrual cycles, e.g. in unexplained or poorly explained fertility, her fertility specialist may recommend ovulation induction medication in an attempt to increase the chance of pregnancy.
Objective: Objective of my study was to determine outcomes of pregnancy (in terms of miscarriages and multiple pregnancies) in primigravidas with successful ovulation induction
Study Design: Descriptive case study
Setting: This study was carried out in department of obstetrics and gynaecology of Nisthar Hospital Multan. 
Duration of Study: This study was conducted from 1st September 2015 to 1st February 2016.
Subjects and methods: A total of 135 infertile women with successful ovulation induction at gestational age of 9 weeks were included in the study. Women conceiving after IUI or IVF, previous history of Diabetes in medical record, Medical history of Hypertension, heart diseases and malignancies were excluded. These studies cases were checked for any abortion and multiple pregnancies by ultrasound at gestational age of 9 weeks. These study cases was followed for four months for final outcome evaluation. All information was recorded.
Results: Age range in this study was from 25 to 35 years with mean age of 31.296±2.83 years and gestational age of 18.400±4.05. Multiple pregnancies was seen in 10(7.4%) patients. Spontaneous miscarriage was seen in 51(37.8%) patients.
Conclusion: It is concluded that patients taking ovulation induction has association with high multiple births miscarriages. Assisted reproduction techniques can largely benefit couples with infertility, but doctors must be aware of the possible consequences and medical risks of these procedures and consequently inform their patients properly. They should be cautious in prescribing drugs that induce ovulation, in spite of the heavy pressure exerted on them by the public.
Keywords:
Ovulation induction, Multiple pregnancies, Spontaneous miscarriage